Synthesis of 3,3-dichloroindolin-2-ones from isatin-3-hydrazones and (dichloroiodo)benzene.
نویسندگان
چکیده
Aryl- and N-substituted isatins were converted to isatin-3-hydrazones and subjected to a dichlorination reaction with PhICl2. Lewis base-catalysis was key to the reaction occurring rapidly and chemoselectively, providing 3,3-dichloroindolin-2-ones in 49-99% yield, and offering a new approach to the deoxygenative dihalogenation reaction.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 3 شماره
صفحات -
تاریخ انتشار 2015